Striker Kevin Doyle is back to full fitness, but Ibrahima Sonko and Bobby Convey are both out for the season.
Portsmouth are without three key players - Lauren (thigh), Pedro Mendes (ankle) and Sean Davis (suspended).
Noe Pamarot (back) is a doubt but Dejan Stefanovic is back in the squad following a knee operation.
Reading (from): Hahnemann, Murty, Halford, de la Cruz, Gunnarsson, Bikey, Ingimarsson, Shorey, Little, Sidwell, Harper, Hunt, Lita, Kitson, Doyle, Long, Federici, Duberry, Sodje, Bennett, Oster, Seol.
Portsmouth (from): James; Johnson, Primus, Stefanovic, Campbell, Traore, Pamarot, O'Brien, O'Neil, Hughes, Kranjcar, Taylor, Kanu, LuaLua, Cole, Benjani, Douala, Mvuemba, Todorov, Ashdown.